Reply to Campos and Munoz: Why phosphate is a bad buffer for guanidinium chloride titrations
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Reply to Campos and Muñoz: Why phosphate is a bad buffer for guanidinium chloride titrations.
Liu et al. (1) alleged that they could not repeat our work on the protein BBL (Protein Data Bank ID code 1W4H) at the most basic level. Campos and Muñoz now admit (2), as we explained (3), that they used a phosphate buffer that greatly changed pH during the guanidinium chloride (GdmCl) titration relative to our Mops buffer. They can now repeat our work. However, the authors now claim (2), misle...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2013
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1303286110